ALFONOLAC™ (Lactose Monohydrate)

The most common way to obtain lactose in solid form is crystallizing from
solution. When crystallization is performed at temperatures below 93.5°C, exclusively α-lactose monohydrate is obtained. α-Lactose has the peculiarity that in the crystalline state each lactose molecule is associated with one molecule of water, i.e. monohydrate. The water is incorporated in the crystal lattice and forms an integral part of it. It is not removed by normal drying processes. Due to this water of crystallization the normal water content of α-lactose monohydrate is around 5%. Only at temperatures as high as 140°C, the crystal water will be removed completely.

In the pharmaceutical industry this lactose is used chiefly as an excipient in the production of solid dosage forms, e.g. tablet production by wet granulation and direct compression and for encapsulation. In dry powder inhalers α–lactose monohydrate is used as a carrier.

INHALATION GRADE OF LACTOSE (Lactose Monohydrate)

The most common way to obtain lactose in solid form is crystallizing from
solution. When crystallization is performed at temperatures below 93.5°C, exclusively α-lactose monohydrate is obtained. α-Lactose has the peculiarity that in the crystalline state each lactose molecule is associated with one molecule of water, i.e. monohydrate. The water is incorporated in the crystal lattice and forms an integral part of it. It is not removed by normal drying processes.

In the pharmaceutical industry this lactose is used chiefly as an excipient in the production of solid dosage forms, e.g. tablet production by wet granulation and direct compression and for encapsulation. In dry powder inhalers α–lactose monohydrate is used as a carrier.

Inhalation Grades : DIPLAC™ 0610, DIPLAC™ 0101, DIPLAC™ 1001, DIPLAC™ 2001, DIPLAC™ 2101, DIPLAC™ 2301, DIPLAC™ 2311, DIPLAC™ 2511, DIPLAC™ 4001, DIPLAC™ 5001

ANHYLAC™ (Lactose Anhydrous)

Pharmaceutical Lactose

When a highly concentrated solution of lactose is crystallized at high temperatures crystals of β-lactose are exclusively formed. Particles with crystalline β-lactose are more brittle than β–lactose monohydrate crystals and they do notcontain crystal water. β-Lactose is often referred to as anhydrous lactose.

The isomeric purity is approximately 80% β-lactose, the remaining 20% being anhydrous α-lactose. Crystals of β-lactose in this product are very small

This type of lactose is used mainly as filler-binder for tablet production by direct compression.

Anhydrous Grades : ANHYLAC™ 005, ANHYLAC™ 006

SPRAYLAC™ (Spray Dried )

Pharmaceutical Lactose

When a highly concentrated lactose solution is spray dried, a glassy, amorphous lactose mass is obtained. This amorphous mass contains both α- and β- lactose, the ratio being approximately the same as the equilibrium ratio of the original lactose solution.

Spray dried lactose is used mainly for tablet manufacture by direct compression processes.

Spray Dried Grades : SPRAYLAC™ 35, SPRAYLAC™ 50, SPRAYLAC™ 55, SPRAYLAC™ 65, SPRAYLAC™ 70, SPRAYLAC™ 75, SPRAYLAC™ 80, SPRAYLAC™ 85, SPRAYLAC™ 90, SPRAYLAC™ 95, SPRAYLAC™ 105